For research use only
| Cat No. | ABC-TC4274 |
| Product Type | Immune Cells |
| Cell Type | Mononuclear Cell |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Disease | Waldenstrom’s Macroglobunemia |
| Storage | Liquid Nitrogen |
Waldenstrom’s Macroglobunemia Bone Marrow Mononuclear Cells, untreated, support lymphoma immunology, biomarker discovery, and therapy evaluation.
Waldenstrom’s Macroglobulinemia (WM) Bone Marrow Mononuclear Cells, Untreated, are density separated by Ficoll-Paque to enrich mononuclear cells from the bone marrow of patients diagnosed with WM. Bone marrow mononuclear cells (BMMCs) are a heterogeneous population consisting of lymphocytes, monocytes, and hematopoietic progenitor cells. They are commonly used to study B-cell receptor signaling, MYD88 L265P mutation-driven oncogenesis, and interactions between malignant clones and the bone marrow niche. In vitro, these cells cannot be repeated freezing and thawing during culture should be avoided. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Waldenstrom’s Macroglobulinemia Bone Marrow Mononuclear Cells-Untreated, WM Bone Marrow MNCs, Waldenstrom BM Mononuclear Cells |
| Species | Human |
| Cat.No | ABC-TC4274 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Mononuclear Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Disease | Waldenstrom’s Macroglobunemia |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Immune Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Waldenstrom’s Macroglobulinemia Bone Marrow Mononuclear Cells can be used as an in vitro model to investigate the mechanisms of abnormal IgM secretion and bone marrow infiltration by malignant B cells. These cells allow researchers to explore the pathophysiology of lymphoplasmacytic lymphoma, including tumor microenvironment interactions and therapeutic response. This model is particularly useful in studies focused on immune dysregulation and drug resistance in hematologic malignancies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).