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Primary Cells

Waldenstrom’s Macroglobunemia Bone Marrow Mononuclear Cells, Untreated

  • For research use only

Cat No.

ABC-TC4274

Product Type

Immune Cells

Cell Type

Mononuclear Cell

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Waldenstrom’s Macroglobunemia

Storage

Liquid Nitrogen

Waldenstrom’s Macroglobunemia Bone Marrow Mononuclear Cells, untreated, support lymphoma immunology, biomarker discovery, and therapy evaluation.

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Description

Waldenstrom’s Macroglobulinemia (WM) Bone Marrow Mononuclear Cells, Untreated, are density separated by Ficoll-Paque to enrich mononuclear cells from the bone marrow of patients diagnosed with WM. Bone marrow mononuclear cells (BMMCs) are a heterogeneous population consisting of lymphocytes, monocytes, and hematopoietic progenitor cells. They are commonly used to study B-cell receptor signaling, MYD88 L265P mutation-driven oncogenesis, and interactions between malignant clones and the bone marrow niche. In vitro, these cells cannot be repeated freezing and thawing during culture should be avoided. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Waldenstrom’s Macroglobulinemia Bone Marrow Mononuclear Cells-Untreated, WM Bone Marrow MNCs, Waldenstrom BM Mononuclear Cells

Species

Human

Cat.No

ABC-TC4274

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Mononuclear Cell

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Waldenstrom’s Macroglobunemia

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Immune Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Waldenstrom’s Macroglobulinemia Bone Marrow Mononuclear Cells can be used as an in vitro model to investigate the mechanisms of abnormal IgM secretion and bone marrow infiltration by malignant B cells. These cells allow researchers to explore the pathophysiology of lymphoplasmacytic lymphoma, including tumor microenvironment interactions and therapeutic response. This model is particularly useful in studies focused on immune dysregulation and drug resistance in hematologic malignancies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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