Transfected Stable Cell Lines

Xpress™ Human AKR1B1 Over-expressing Cell Line (HCC827)

  • For research use only

Cat No.

ABC-X0183C

Product Type

Overexpression Stable Cell Lines

Cell Type

Epithelial

Species

Human

Host Cell

HCC827

Source Organ

Lung

Disease

Adenocarcinoma

Storage

Liquid Nitrogen

The overexpression cell line provides an ideal model for studying tumor progression and drug resistance, supporting personalized research projects.

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Description

AKR1B1 HCC827 Overexpression Cell Line is a genetically engineered model derived from selected human lung adenocarcinoma (HCC827) parental cell line based on customers’ requirement. AKR1B1 HCC827 overexpression cell line is generated by stable integration of exogenous human AKR1B1 into HCC827 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The AKR1B1 gene encodes aldose reductase, which functions in the detoxification of aldehydes and contributes to metabolic stress adaptation. Its overexpression is associated with tumor progression, chemoresistance, and diabetic pathologies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0183C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Lung

Disease

Adenocarcinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

HCC827

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The AKR1B1 HCC827 Overexpression Cell Line provides a disease-relevant model for evaluating AKR1B1-related oncogenic mechanisms, drug resistance, and anti-diabetic or anticancer therapeutic compounds.

Inquiring Xpress™ Human AKR1B1 Over-expressing Cell Line (HCC827)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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