Transfected Stable Cell Lines

Xpress™ Human AKR1B1 Over-expressing Cell Line (NCI-H1975)

  • For research use only

Cat No.

ABC-X0182C

Product Type

Overexpression Stable Cell Lines

Cell Type

Epithelial

Species

Human

Host Cell

NCI-H1975

Source Organ

Lung

Disease

Lung Adenocarcinoma

Storage

Liquid Nitrogen

The AKR1B1 NCI-H1975 overexpression cell line is custom-designed for cancer research, supporting in-depth exploration and drug development.

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Description

AKR1B1 NCI-H1975 Overexpression Cell Line is a genetically engineered model derived from selected human non-small cell lung cancer (NCI-H1975) parental cell line based on customers’ requirement. AKR1B1 NCI-H1975 overexpression cell line is generated by stable integration of exogenous human AKR1B1 into NCI-H1975 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The AKR1B1 gene encodes aldose reductase, an enzyme involved in the polyol pathway and oxidative stress response. It is linked to diabetic complications, inflammation, and cancer chemoresistance. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0182C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Lung

Disease

Lung Adenocarcinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

NCI-H1975

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The AKR1B1 NCI-H1975 Overexpression Cell Line enables research in cancer biology, redox regulation, and pharmacological screening of aldose reductase inhibitors in a lung cancer context.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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