For research use only
| Cat No. | ABC-X0182C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | NCI-H1975 |
| Source Organ | Lung |
| Disease | Lung Adenocarcinoma |
| Storage | Liquid Nitrogen |
The AKR1B1 NCI-H1975 overexpression cell line is custom-designed for cancer research, supporting in-depth exploration and drug development.
AKR1B1 NCI-H1975 Overexpression Cell Line is a genetically engineered model derived from selected human non-small cell lung cancer (NCI-H1975) parental cell line based on customers’ requirement. AKR1B1 NCI-H1975 overexpression cell line is generated by stable integration of exogenous human AKR1B1 into NCI-H1975 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The AKR1B1 gene encodes aldose reductase, an enzyme involved in the polyol pathway and oxidative stress response. It is linked to diabetic complications, inflammation, and cancer chemoresistance. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0182C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Lung |
| Disease | Lung Adenocarcinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | NCI-H1975 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The AKR1B1 NCI-H1975 Overexpression Cell Line enables research in cancer biology, redox regulation, and pharmacological screening of aldose reductase inhibitors in a lung cancer context.