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Xpress™ Human ARV7 Over-expressing Cell Line (HEK293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human ARV7 Over-expressing Cell Line (HEK293T)
Species

Human
Cat.No

ABC-X0246C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

HEK293T

Description

ARV7 HEK293T Overexpression Cell Line is a customized human model derived from HEK293T cells for prostate cancer-related research. ARV7 HEK293T overexpression is achieved by lentiviral-mediated integration of full-length ARV7 cDNA. Stable expression is confirmed by qRT-PCR. Cells are cultured at low passage numbers (<P20). Target ARV7 is an androgen receptor splice variant lacking the ligand-binding domain but retaining transcriptional activity. It is associated with castration-resistant prostate cancer (CRPC), mediating resistance to androgen receptor-targeted therapies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model enables functional studies of ARV7-mediated transcriptional regulation in CRPC and supports high-throughput screening for novel ARV7-targeted therapeutics and diagnostic tools.

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