For research use only
| Cat No. | ABC-X0246C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | HEK293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The Xpress™ Human ARV7 over-expressing cell line (HEK293T) enable functional analysis of androgen receptor variants in prostate cancer research.
ARV7 HEK293T Overexpression Cell Line is a customized human model derived from HEK293T cells for prostate cancer-related research. ARV7 HEK293T overexpression is achieved by lentiviral-mediated integration of full-length ARV7 cDNA. Stable expression is confirmed by qRT-PCR. Cells are cultured at low passage numbers (<P20). Target ARV7 is an androgen receptor splice variant lacking the ligand-binding domain but retaining transcriptional activity. It is associated with castration-resistant prostate cancer (CRPC), mediating resistance to androgen receptor-targeted therapies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.
| Species | Human |
| Cat.No | ABC-X0246C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | HEK293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This model enables functional studies of ARV7-mediated transcriptional regulation in CRPC and supports high-throughput screening for novel ARV7-targeted therapeutics and diagnostic tools.