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Xpress™ Human B7H3 Over-expressing Cell Line (CT26)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human B7H3 Over-expressing Cell Line (CT26)
Species

Human
Cat.No

ABC-X0114C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Colon
Disease

Colorectal Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CT26

Description

Xpress™ Human B7H3 over-expressing cell line (CT26) is a genetically engineered model derived from selected murine CT26 parental cell line based on customers’ requirement. Human B7H3 overexpression cell line is generated by stable integration of exogenous human B7H3 gene (CD276) into CT26 host cells using our optimized transduction of lentiviral vectors.
Target
B7H3 is a member of the B7 superfamily of immune checkpoint molecules, with immunomodulatory roles in cancer and inflammation. It is overexpressed in a broad range of tumors and is a promising target for immunotherapies. AcceGen offers generation of stable checkpoint ligand models in syngeneic murine systems. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Human B7H3 over-expressing cell line (CT26) serves as a key model for studying immune evasion and testing B7H3-targeted therapies in murine tumor models. It supports syngeneic preclinical research and checkpoint blockade evaluation.

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