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Xpress™ Human B7H4 Over-expressing Cell Line (MC38)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human B7H4 Over-expressing Cell Line (MC38)
Species

Human
Cat.No

ABC-X0156C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38

Description

Xpress™ Human B7H4 over-expressing cell line (MC38) is a genetically engineered model derived from selected murine colon adenocarcinoma MC38 parental cell line based on customers’ requirement. B7H4 MC38 overexpression cell line is generated by stable integration of exogenous human B7H4 into MC38 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The FCAR gene (also known as CD89) encodes the Fc alpha receptor for IgA, which mediates immune effector functions such as phagocytosis and cytokine release. It plays critical roles in mucosal immunity, autoimmune diseases, and antibody-based therapy responses. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The B7H4 MC38 Overexpression Cell Line is designed for tumor immune escape studies in colorectal cancer models and facilitates evaluation of B7H4-targeting therapeutics in syngeneic mouse systems.

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