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Xpress™ Human CCKBR Over-expressing Cell Line (A431)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CCKBR Over-expressing Cell Line (A431)
Species

Human
Cat.No

ABC-X0166C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Skin
Disease

Epidermoid Cancer
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

A431

Description

CCKBR A431 Overexpression Cell Line was constructed by lentiviral transduction of human CCKBR cDNA into A431 epidermoid carcinoma cells. The inserted expression cassette is stably integrated and validated by gene-level assays.
Target
CCKBR (Cholecystokinin B Receptor) is a G protein-coupled receptor that binds gastrin and cholecystokinin. It regulates gastric acid secretion, cell growth, and anxiety-related behavior. Overexpression of CCKBR is found in gastrointestinal and small cell lung cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The CCKBR A431 Overexpression Cell Line supports research in GPCR signaling, cancer cell proliferation, and drug discovery involving gastrin/CCK signaling pathways. It is suited for antagonist screening and tumor biology investigations.

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