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Transfected Stable Cell Lines

Xpress™ Human CD39 Over-expressing Cell Line (MC38)

  • For research use only

Cat No.

ABC-X0138C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial-like
Species

Human
Host Cell

MC38
Source Organ

Colon
Disease

Colon Adenocarcinoma
Storage

Liquid Nitrogen

The Xpress™ Human CD39 Overexpressing Cell Line (MC38) is an important model for researching immune tolerance and tumor microenvironment interactions.

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  • Xpress™ Human CD39 Over-expressing Cell Line (MC38)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CD39 Over-expressing Cell Line (MC38)

Description

Xpress™ Human CD39 over-expressing cell line (MC38) is a genetically engineered model derived from selected murine MC38 parental cell line based on customers’ requirement. Human CD39 overexpression cell line is generated by stable integration of exogenous human CD39 gene into MC38 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD39 is an immunosuppressive enzyme that acts upstream of CD73 in the adenosinergic pathway, promoting tumor growth and immune evasion. It is considered a potential target for reversing T cell exhaustion and enhancing antitumor immunity in solid tumors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0138C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Xpress™ Human CD39 over-expressing cell line (MC38) supports detailed mechanistic studies on purinergic signaling and immune modulation. It is ideal for preclinical evaluation of CD39-blocking agents and combination immunotherapies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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