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Xpress™ Human CLDN1 Over-expressing Cell Line (MC38)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CLDN1 Over-expressing Cell Line (MC38)
Species

Human
Cat.No

ABC-X0412C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38

Description

Human CLDN1 MC38 Overexpression Cell Line is a genetically engineered model derived from selected murine colon adenocarcinoma (MC38) parental cell line based on customers’ requirement. Human CLDN1 MC38 overexpression cell line is generated by stable integration of exogenous human CLDN1 into MC38 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CLDN1 is a critical component of epithelial tight junctions and is involved in maintaining cell polarity and barrier function. Its upregulation is associated with invasive cancer phenotypes and poor prognosis in several human cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This system allows human CLDN1 function to be studied in immune-competent murine models, supporting translational research in metastasis, epithelial-mesenchymal transition (EMT), and anti-CLDN1 immunotherapy strategies.

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