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Xpress™ Human EP4 Over-expressing Cell Line (HEK293)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human EP4 Over-expressing Cell Line (HEK293)
Species

Human
Cat.No

ABC-X0147C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

HEK293

Description

Xpress™ Human EP4 over-expressing cell line (HEK293) is a genetically engineered model derived from selected human embryonic kidney HEK293 parental cell line based on customers’ requirement. EP4 HEK293 overexpression cell line is generated by stable integration of exogenous human EP4 (PTGER4) into HEK293 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The EP4 receptor, encoded by PTGER4, is a G-protein-coupled receptor for prostaglandin E2 (PGE2), involved in inflammation, angiogenesis, and tumor progression. EP4 overexpression is linked to immunosuppression and metastasis in breast and colorectal cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The EP4 HEK293 Overexpression Cell Line is suited for screening of EP4 antagonists, understanding PGE2 signaling in inflammation and cancer, and assessing GPCR-related pathway modulation.

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