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Xpress™ Human FGFR3IIIc Over-expressing Cell Line (BAF3)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human FGFR3IIIc Over-expressing Cell Line (BAF3)
Species

Human
Cat.No

ABC-X0116C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Xpress™ Human FGFR3IIIc over-expressing cell line (BAF3) is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. Human FGFR3IIIc overexpression cell line is generated by stable integration of exogenous human FGFR3IIIc isoform into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
FGFR3IIIc is an alternatively spliced isoform of the FGFR3 receptor that shows distinct ligand-binding specificity and is implicated in tissue-specific signaling. It plays a key role in development, skeletal dysplasia, and cancer progression. AcceGen offers generation of isoform-specific overexpression models for dissecting functional consequences of alternative splicing. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Human FGFR3IIIc over-expressing cell line (BAF3) is ideal for studying isoform-specific receptor function, oncogenic signaling, and targeted drug responses in hematopoietic models. It supports high-throughput screening and functional assays of FGFR-targeted therapies.

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