For research use only
| Cat No. | ABC-X0169C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The FZD10 CHOK1 overexpression cell line is a key tool for studying the Wnt signaling pathway, suitable for drug screening and tumor mechanism research.
FZD10 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. FZD10 CHOK1 overexpression cell line is generated by stable integration of exogenous human FZD10 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The FZD10 gene encodes a seven-transmembrane domain protein of the Frizzled family that functions as a receptor in the Wnt signaling pathway. FZD10 overexpression is implicated in the progression of synovial sarcoma, colorectal cancer, and gastric cancer, where it promotes tumor proliferation, migration, and resistance to apoptosis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0169C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The FZD10 CHOK1 Overexpression Cell Line serves as a valuable model for investigating Wnt/β-catenin signaling activation and downstream oncogenic transcription. It is suitable for drug screening targeting Wnt pathway receptors and elucidating tumor cell survival mechanisms.