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Xpress™ Human FZD4 Over-expressing Cell Line (CT26)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human FZD4 Over-expressing Cell Line (CT26)
Species

Human
Cat.No

ABC-X0434C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Colon
Disease

Colorectal Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CT26

Description

Xpress™ Human FZD4 CT26 Overexpression Cell Line is a genetically engineered model derived from mouse colon carcinoma (CT26) parental cells based on customers’ requirements. The overexpression cell line is generated by stable lentiviral integration of the full-length human FZD4 gene into CT26 host cells. Overexpression clone is validated at gene level by qRT-PCR.
Target
Frizzled-4 (FZD4) is a Wnt receptor that plays a critical role in Wnt/β-catenin signaling pathway, vascular development, and retinal angiogenesis. Dysregulation of FZD4 is associated with diseases such as familial exudative vitreoretinopathy and cancer.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Human FZD4 CT26 Overexpression Cell Line is useful for studying Wnt signaling, vascular biology, and for evaluating Wnt/FZD-targeted drug candidates.

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