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Transfected Stable Cell Lines

Xpress™ Human GPC3 Over-expressing Cell Line (EL4)

  • For research use only

Cat No.

ABC-X0419C
Product Type

Overexpression Stable Cell Lines
Cell Type

T lymphocyte
Species

Human
Host Cell

EL4
Source Organ

Thymus
Disease

Lymphoma
Storage

Liquid Nitrogen

EL4 cells with human GPC3 overexpression, designed for tumor immunology studies, therapeutic target screening, and T cell engagement assays.

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  • Xpress™ Human GPC3 Over-expressing Cell Line (EL4)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human GPC3 Over-expressing Cell Line (EL4)

Description

Human GPC3 EL4 Overexpression Cell Line is a genetically engineered model derived from selected murine T lymphoma (EL4) parental cell line based on customers’ requirement. Human GPC3 EL4 overexpression cell line is generated by stable integration of exogenous human GPC3 into EL4 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
GPC3 is a cell surface proteoglycan associated with embryonic development and tumorigenesis. It is frequently overexpressed in hepatocellular carcinoma and has become a target for precision immunotherapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0419C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

T lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Thymus
Disease

Lymphoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

EL4
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model allows expression of human GPC3 in a murine immune background, facilitating immunogenicity studies, therapeutic antibody screening, and evaluation of GPC3-targeted therapies in immune-competent systems.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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