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Transfected Stable Cell Lines

Xpress™ Human GPC3 Over-expressing Cell Line (EL4)

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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-X0419C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

T lymphocyte

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Thymus

Disease

Lymphoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

EL4

Description

Human GPC3 EL4 Overexpression Cell Line is a genetically engineered model derived from selected murine T lymphoma (EL4) parental cell line based on customers’ requirement. Human GPC3 EL4 overexpression cell line is generated by stable integration of exogenous human GPC3 into EL4 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
GPC3 is a cell surface proteoglycan associated with embryonic development and tumorigenesis. It is frequently overexpressed in hepatocellular carcinoma and has become a target for precision immunotherapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • This model allows expression of human GPC3 in a murine immune background, facilitating immunogenicity studies, therapeutic antibody screening, and evaluation of GPC3-targeted therapies in immune-competent systems.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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