For research use only
| Cat No. | ABC-X0228C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The Xpress™ Human GPRC5C Overexpression Cell Line (293T) enables functional studies of orphan GPCR signaling and its roles in metabolic and cancer biology.
The human GPRC5C overexpression cell line (293T) was created by integrating exogenous GPRC5C cDNA into the 293T host genome using lentiviral delivery. qRT-PCR confirms stable expression, and the cells are propagated under selective pressure to ensure genetic consistency.
Target
GPRC5C is a member of the type 3 G protein-coupled receptor family and is thought to participate in glucose metabolism and pancreatic islet function. Altered GPRC5C expression has been linked to metabolic disorders and pancreatic tumor biology. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0228C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This model supports the investigation of GPRC5C’s signaling roles in endocrine systems and metabolic disease progression. It is ideal for drug screening and mechanistic pathway analysis involving GPCRs.