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Xpress™ Human hERG Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human hERG Over-expressing Cell Line (CHOK1)
Species

Human
Cat.No

ABC-X0259C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Xpress™ Human hERG Overexpression Cell Line (CHOK1) is a genetically engineered model derived from selected Chinese hamster ovary CHOK1 parental cell line based on customers’ requirement. hERG CHOK1 overexpression cell line is generated by stable integration of exogenous human hERG (KCNH2) into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
hERG (human Ether-à-go-go-Related Gene, KCNH2) encodes a potassium channel essential for cardiac repolarization. Mutations or drug-induced blockade of hERG are linked to long QT syndrome and arrhythmias.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The hERG CHOK1 Overexpression Cell Line is used for cardiotoxicity screening and assessment of hERG channel activity. It supports drug safety testing in preclinical development and mechanistic studies of cardiac electrophysiology.

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