Xpress™ Human ICAM1 Over-expressing Cell Line (CT26)

Description

ICAM1 CT26 Overexpression Cell Line is a genetically engineered model derived from murine colon carcinoma CT26 cells. The stable ICAM1 overexpression was achieved by lentiviral transduction of full-length human ICAM1 cDNA. The expression cassette is integrated into the genome and selected under optimal antibiotic pressure. Validated by qRT-PCR and low-passage (<P20) preservation ensures cell line stability. Target ICAM1 (Intercellular Adhesion Molecule 1) is a cell surface glycoprotein involved in leukocyte adhesion and transmigration. It plays a critical role in inflammatory responses, immune surveillance, and tumor–immune interaction. Aberrant ICAM1 expression has been linked to colorectal cancer metastasis, chronic inflammation, and immune evasion. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.