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Xpress™ Human ICAM1 Over-expressing Cell Line (MC38)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human ICAM1 Over-expressing Cell Line (MC38)
Species

Human
Cat.No

ABC-X0363C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38

Description

ICAM1 MC38 Overexpression Cell Line is a genetically engineered model derived from selected murine colon adenocarcinoma (MC38) parental cell line based on customers’ requirement. ICAM1 MC38 overexpression cell line is generated by stable integration of exogenous human ICAM1 into MC38 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The ICAM1 gene encodes a cell surface adhesion molecule that plays key roles in leukocyte trafficking and immune responses. It is upregulated in inflammatory conditions and various malignancies, including colorectal and breast cancers. ICAM1-mediated interactions facilitate tumor infiltration by immune cells and have therapeutic implications in inflammation and immuno-oncology. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The ICAM1 MC38 Overexpression Cell Line serves as a powerful tool to investigate ICAM1-associated immunological pathways and tumor-immune interactions. This model enables mechanistic studies of immune cell adhesion, signaling, and cancer immunotherapy responses. It is utilized for evaluating ICAM1-targeted treatments and immune checkpoint strategies in preclinical research.

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