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Xpress™ Human IL21R Over-expressing Cell Line (BAF3)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human IL21R Over-expressing Cell Line (BAF3)
Species

Human
Cat.No

ABC-X0275C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Xpress™ Human IL21R Overexpression Cell Line is a genetically engineered model derived from selected murine pro-B (BAF3) parental cell line based on customers’ requirement. IL21R BAF3 overexpression cell line is generated by stable integration of exogenous human IL21R into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The IL21R gene encodes a receptor for interleukin-21, regulating immune cell proliferation, differentiation, and cytotoxic function. It is vital for T-cell, B-cell, and NK cell responses and is implicated in autoimmune diseases and lymphoid malignancies. IL21R resides at the cell membrane and signals through JAK/STAT pathways. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The IL21R BAF3 Overexpression Cell Line serves as a powerful tool to investigate IL21-mediated immune regulation and its role in hematologic disorders. This model enables evaluation of cytokine responses, antibody production, and cytotoxicity in engineered immune systems. It is widely used in immunotherapy development and receptor-targeted screening.

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