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Xpress™ Human IL2RG Over-expressing Cell Line (CT26)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human IL2RG Over-expressing Cell Line (CT26)
Species

Human
Cat.No

ABC-X0385C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Colon
Disease

Colorectal Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CT26

Description

Xpress™ Human IL2RG Overexpression Cell Line is a genetically engineered model derived from selected murine CT26 parental cell line based on customers’ requirement. IL2RG overexpression cell line is generated by stable integration of exogenous human IL2RG into CT26 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The IL2RG gene encodes the common gamma chain receptor involved in the signaling of multiple interleukins, essential for lymphocyte development. Its dysfunction is associated with severe combined immunodeficiency (SCID). AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The IL2RG CT26 Overexpression Cell Line is a valuable tool to study gamma-chain cytokine signaling, T and NK cell responses, and immune modulation in cancer and immunodeficiency models. It enables preclinical evaluation of IL2RG-targeted immunotherapies and cytokine-based treatments.

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