For research use only
| Cat No. | ABC-X0143C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | HEK293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The MMP7 HEK293T cell line is specifically designed for studying extracellular matrix remodeling and cancer invasion, supporting experimental needs.
Xpress™ Human MMP7 over-expressing cell line (HEK293T) is a genetically engineered model derived from selected human embryonic kidney 293T parental cell line based on customers’ requirement. MMP7 HEK293T overexpression cell line is generated by stable integration of exogenous human MMP7 into HEK293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The MMP7 gene encodes matrix metallopeptidase 7, a zinc-dependent protease that degrades components of the extracellular matrix and is crucial for tissue remodeling, inflammation, and cancer metastasis. MMP7 is overexpressed in colorectal, pancreatic, and lung cancers, where it facilitates invasion, angiogenesis, and tumor growth via ECM breakdown and signaling molecule activation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0143C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | HEK293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The MMP7 HEK293T Overexpression Cell Line serves as a robust model to study extracellular matrix remodeling and cancer invasion. It enables screening of MMP7 inhibitors, functional assays for metastasis-related pathways, and investigation of tumor microenvironment modulation.