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Xpress™ Human NKG2A Over-expressing Cell Line (HEK293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human NKG2A Over-expressing Cell Line (HEK293T)
Species

Human
Cat.No

ABC-X0136C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

HEK293T

Description

Xpress™ Human NKG2A over-expressing cell line is a genetically engineered model derived from selected HEK293T parental cell line based on customers’ requirement. Human NKG2A overexpression cell line is generated by stable integration of exogenous human NKG2A (KLRC1) into HEK293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
NKG2A is an inhibitory receptor expressed on NK and CD8+ T cells. It binds HLA-E and downregulates cytotoxic responses, contributing to immune tolerance. NKG2A is considered a checkpoint molecule in cancer immunotherapy, especially in combination with PD-1/PDL1 blockade. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The NKG2A HEK293T Overexpression Cell Line is designed to support functional studies of NK cell inhibition, checkpoint blockade evaluation, and development of NKG2A-targeted therapeutics.

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