For research use only
| Cat No. | ABC-X0168C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The Norrin 293T overexpression cell line, with stable clone validation, is suitable for studying retinal diseases and related therapeutic strategies.
Norrin 293T Overexpression Cell Line is generated via lentiviral transduction of human Norrin (NDP) cDNA into 293T cells. Stable clones were screened and verified for gene expression by qRT-PCR.
Target
Norrin is a secreted protein involved in retinal vascular development and neural function, acting through the Frizzled-4 receptor in the Wnt/β-catenin signaling pathway. Mutations are associated with Norrie disease and familial exudative vitreoretinopathy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0168C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Norrin 293T Overexpression Cell Line is used to study angiogenesis, retinal development, and Wnt signaling modulation. It supports assays for therapeutic development in vascular and neurodegenerative disorders.