For research use only
| Cat No. | ABC-X0199C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The Xpress™ Human PLXNB2 Overexpression Cell Line (293T) supports mechanistic studies on semaphorin signaling, cancer progression, and cell migration.
Human PLXNB2 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney 293T parental cell line based on customers’ requirement. PLXNB2 293T overexpression cell line is generated by stable integration of exogenous human PLXNB2 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT‑PCR.
Target
The PLXNB2 gene encodes Plexin‑B2, another semaphorin receptor regulating neural development, angiogenesis, and tumor cell motility. Elevated PLXNB2 expression correlates with poor prognosis in glioma and breast cancer, driving EMT and invasive growth. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0199C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The PLXNB2 293T Overexpression Cell Line provides an in‑vitro system to explore semaphorin‑induced signaling cascades, EMT mechanisms, and to screen biologics or small‑molecule modulators of Plexin‑B2 for anticancer therapy.