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Transfected Stable Cell Lines

Xpress™ Human PVRL2b Over-expressing Cell Line (293T)

  • For research use only

Cat No.

ABC-X0376C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

293T
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

293T cells stably expressing human PVRL2b, suitable for cell-cell adhesion research, tumor immunology, and the role of nectin family in immune evasion.

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  • Xpress™ Human PVRL2b Over-expressing Cell Line (293T)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human PVRL2b Over-expressing Cell Line (293T)

Description

PVRL2b 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. PVRL2b 293T overexpression cell line is generated by stable integration of exogenous human PVRL2b into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The PVRL2b gene encodes a member of the nectin family involved in cell adhesion and immune regulation. PVRL2b plays a role in intercellular junction formation and interacts with immune checkpoint molecules such as TIGIT and CD96, contributing to immune cell modulation in tumor microenvironments. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0376C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The PVRL2b 293T Overexpression Cell Line serves as a powerful tool to study nectin-mediated cell adhesion and immune checkpoint biology. This model is valuable for dissecting immune evasion pathways in cancer and for developing therapeutic strategies targeting PVRL2b-TIGIT interactions.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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