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Xpress™ Human PVRL2b Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human PVRL2b Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0376C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

PVRL2b 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. PVRL2b 293T overexpression cell line is generated by stable integration of exogenous human PVRL2b into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The PVRL2b gene encodes a member of the nectin family involved in cell adhesion and immune regulation. PVRL2b plays a role in intercellular junction formation and interacts with immune checkpoint molecules such as TIGIT and CD96, contributing to immune cell modulation in tumor microenvironments. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The PVRL2b 293T Overexpression Cell Line serves as a powerful tool to study nectin-mediated cell adhesion and immune checkpoint biology. This model is valuable for dissecting immune evasion pathways in cancer and for developing therapeutic strategies targeting PVRL2b-TIGIT interactions.

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