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Transfected Stable Cell Lines

Xpress™ Mouse B7H4 Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0400C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Mouse
Host Cell

CHOK1
Source Organ

Ovary
Disease

Normal
Storage

Liquid Nitrogen

CHOK1 cell line with stable mouse B7H4 expression, optimized for immune checkpoint, cancer biology, and therapeutic antibody screening assays.

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  • Xpress™ Mouse B7H4 Over-expressing Cell Line (CHOK1)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse B7H4 Over-expressing Cell Line (CHOK1)

Description

Mouse B7H4 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. Mouse B7H4 CHOK1 overexpression cell line is generated by stable integration of exogenous mouse B7H4 (VTCN1) into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
B7H4 (VTCN1) is an immune checkpoint molecule belonging to the B7 family that plays a negative regulatory role in T-cell-mediated immune responses. Its upregulation has been observed in various cancers, where it contributes to immune suppression and tumor escape. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Mouse
Cat.No

ABC-X0400C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This overexpression model is ideal for research into immune checkpoint regulation, tumor immune evasion, and immunotherapy development. It can support studies on antibody generation, pathway analysis, and evaluation of novel B7H4-targeted therapeutics in preclinical mouse-relevant models.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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