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Xpress™ Mouse CD22 Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse CD22 Over-expressing Cell Line (CHOK1)
Species

Mouse
Cat.No

ABC-X0401C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Mouse CD22 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. Mouse CD22 CHOK1 overexpression cell line is generated by stable integration of exogenous mouse CD22 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD22 is a B-cell-specific transmembrane glycoprotein that plays a key role in regulating B-cell receptor (BCR) signaling. It functions as an inhibitory co-receptor and is an emerging target in autoimmune diseases and B-cell malignancies such as leukemia and lymphoma.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model system is suited for studying CD22-mediated signaling in B cells and evaluating therapeutic antibodies or inhibitors targeting CD22. It also serves as a platform for preclinical validation of CAR-T constructs and immunomodulatory compounds in B-cell associated disorders.

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