For research use only
| Cat No. | ABC-X0423C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Mouse |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
CHOK1 cells overexpressing mouse IGF1R, suitable for IGF pathway exploration, therapeutic screening, and species-specific antibody validation.
Xpress™ Mouse IGF1R CHOK1 Overexpression Cell Line is a genetically engineered model derived from the Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirements. The overexpression cell line is generated by stable integration of the full-length mouse IGF1R gene into CHOK1 host cells via lentiviral vector transduction. Overexpression clone is validated at gene level by qRT-PCR.
Target
IGF1R (Insulin-like Growth Factor 1 Receptor) is a transmembrane tyrosine kinase receptor that mediates growth and survival signals via the PI3K/AKT and MAPK pathways. Mouse IGF1R plays crucial roles in development, metabolism, and cancer biology. Dysregulated IGF1R signaling is associated with oncogenesis and resistance to apoptosis.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Mouse |
| Cat.No | ABC-X0423C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Mouse IGF1R CHOK1 Overexpression Cell Line is widely used to dissect IGF1R-driven signaling pathways and evaluate targeted inhibitors. This model supports cancer biology studies and drug screening for therapies aimed at IGF1R-related diseases.