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Xpress™ Mouse IGF1R Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse IGF1R Over-expressing Cell Line (CHOK1)
Species

Mouse
Cat.No

ABC-X0423C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Xpress™ Mouse IGF1R CHOK1 Overexpression Cell Line is a genetically engineered model derived from the Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirements. The overexpression cell line is generated by stable integration of the full-length mouse IGF1R gene into CHOK1 host cells via lentiviral vector transduction. Overexpression clone is validated at gene level by qRT-PCR.
Target
IGF1R (Insulin-like Growth Factor 1 Receptor) is a transmembrane tyrosine kinase receptor that mediates growth and survival signals via the PI3K/AKT and MAPK pathways. Mouse IGF1R plays crucial roles in development, metabolism, and cancer biology. Dysregulated IGF1R signaling is associated with oncogenesis and resistance to apoptosis.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Mouse IGF1R CHOK1 Overexpression Cell Line is widely used to dissect IGF1R-driven signaling pathways and evaluate targeted inhibitors. This model supports cancer biology studies and drug screening for therapies aimed at IGF1R-related diseases.

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