For research use only
| Cat No. | ABC-X0427C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Rat |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
293T cells overexpressing rat CD70, ideal for evaluating immune costimulation, antibody development, and cross-species CD70-targeted therapies.
Xpress™ Rat CD70 293T Overexpression Cell Line is a genetically engineered model derived from the human embryonic kidney (HEK293T) parental cell line based on customers’ requirements. The overexpression cell line is generated by stable lentiviral transduction of full-length rat CD70 into 293T host cells. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD70 is a type II transmembrane protein belonging to the tumor necrosis factor (TNF) family, functioning as a costimulatory molecule in T cell activation. Rat CD70 regulates immune responses and is aberrantly expressed in certain hematological malignancies.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Rat |
| Cat.No | ABC-X0427C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Rat CD70 293T Overexpression Cell Line is applied in immunological research to elucidate CD70-mediated signaling and to evaluate targeted therapies against CD70-expressing tumors.