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Transfected Stable Cell Lines

Xpress™ Rat CD73 Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0132C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Rat
Host Cell

CHOK1
Source Organ

Ovary
Disease

Normal
Storage

Liquid Nitrogen

The Xpress™ rat CD73 overexpression cell line is an ideal model for studying immune suppression and developing targeted small molecule inhibitors.

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  • Xpress™ Rat CD73 Over-expressing Cell Line (CHOK1)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Rat CD73 Over-expressing Cell Line (CHOK1)

Description

Xpress™ Rat CD73 over-expressing cell line is a genetically engineered model derived from selected CHOK1 parental cell line based on customers’ requirement. Rat CD73 overexpression cell line is generated by stable integration of exogenous rat CD73 (Nt5e) into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD73 (ecto-5′-nucleotidase, Nt5e) is an enzyme that catalyzes the conversion of extracellular AMP to adenosine, playing a key role in immunosuppression and tumor immune evasion. It is involved in purinergic signaling and contributes to the formation of an immunosuppressive tumor microenvironment. CD73 overexpression has been observed in various cancers, including breast, colorectal, and prostate cancer. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Rat
Cat.No

ABC-X0132C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Rat CD73 CHOK1 Overexpression Cell Line provides a robust model for studying CD73-mediated adenosine signaling and its immunoregulatory roles. It is suitable for evaluating small molecule inhibitors or antibodies targeting CD73 in preclinical screening and immunotherapy development.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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