For research use only
| Cat No. | ABC-TC0003 |
| Product Type | Mouse Myeloma Cell Lines |
| Cell Type | B Cell |
| Species | Hamster |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Disease | Hybridoma |
| Product Code | 2C11 |
Tumorigenecity: Isoenzyme: Histopathology: hybridoma; Mouse(myeloma)Subculture: Cultures can be maintained by addition or replacement of fresh medium.
145-2C11 is a murine hybridoma cell line developed by fusing spleen cells from immunized Armenian hamsters with mouse myeloma cells. The cell line originates from lymphoid tissue and belongs to the B-cell lineage. These hybridoma cells exhibit a round morphology and grow in suspension culture. 145-2C11 cells are known for their stable secretion of high-affinity IgG2b monoclonal antibodies specific to CD3, making them widely used in immunological assays and T-cell activation studies. Cytogenetically, the cells display murine-derived chromosomes with a hybrid karyotype. These cells are tumorigenic in immunocompromised mice.The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | 2C11 |
| Species | Hamster |
| Cat.No | ABC-TC0003 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | B Cell |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Disease | Hybridoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Myeloma Cell Lines |
145-2C11 cells are primarily used for the production of monoclonal antibodies against mouse CD3, a key component of the T-cell receptor complex. These antibodies are essential tools for T-cell activation, depletion, or modulation in immunological research and mouse models of inflammation or autoimmunity. The stable antibody expression of 145-2C11 makes it suitable for large-scale antibody production and downstream functional assays, including flow cytometry, in vivo immunotherapy protocols, and receptor signaling studies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
