Beagle Canine Peripheral Blood Mononuclear Cells

Description

Beagle Canine Peripheral Blood Mononuclear Cells (PBMCs) are primary cells isolated from the whole blood of Beagle dogs using density gradient centrifugation to remove red blood cells. The population consists of various immune cells, including lymphocytes and monocytes, which play an essential role in studying the immune system’s physiological and pathological processes. Beagle PBMCs are valuable for research into immune-mediated diseases, including autoimmune diseases and primary immune deficiency diseases, which have similarities to human immune disorders. These cells are typically cryopreserved using a standardized protocol, ensuring high viability (>80%) after thawing, and are stored at temperatures below -120°C, ideally in liquid nitrogen tanks. However, it is recommended to regularly monitor for potential viral contamination to ensure the safety of the cells in research applications.

Application

• Peripheral Blood Mononuclear Cells (PBMCs) are widely used in experimental studies. They are isolated from peripheral blood and are often employed to assess immune responses. PBMCs are widely applied in trending research areas, for example, multi-omics analysis of PBMCs based on CITE-seq data,in vitro differentiation into cardiomyocytes and vascular-related cells. These cells are ideal for establishing an in vitro PBMC differentiation system that allows you to combine molecular and cytological approaches to study the differentiation mechanisms of PBMCs.