For research use only
| Cat No. | ABC-TC0073 |
| Product Type | Mouse Brain Cancer Cell Lines |
| Cell Type | Endothelial |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Endothelioma |
| Product Code | bEND.3; b.End3; Bend.3; bEnd3; BEND3; brain-derived Endothelial cells.3 |
bEnd.3 Brain Endothelial Cells express vascular markers and support modeling of the blood-brain barrier, angiogenesis, and cerebral vasculature.
bEnd.3 is a mouse endothelial cell line originally derived from the cerebral cortex of a 6-week-old BALB/c mouse with endothelioma. These cells exhibit typical endothelial morphology and adherent growth properties. bEnd.3 cells can be induced by cytokines and lipopolysaccharide (LPS) to express molecules such as Peyer’s junction high endothelial cell receptor, mucosal vascular settlement factor (MAdCAM-1), and endothelial cell selectins. They are positive for various endothelial-specific proteins, including PECAM-1, Endoglin, MECA-32, and Flk-1, as confirmed by Flow Cytometry (FACS) analysis.
| Product Code | bEND.3; b.End3; Bend.3; bEnd3; BEND3; brain-derived Endothelial cells.3 |
| Species | Mouse |
| Cat.No | ABC-TC0073 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Endothelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Endothelioma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Brain Cancer Cell Lines |
The bEnd.3 cell line is a valuable model for both vascular biology and neuroscience research. It plays a crucial role in understanding diseases linked to the lymphatic and vascular systems, including endothelioma. Notably, these cells are particularly widely used to investigate blood-brain barrier (BBB) disruption and to assess potential therapeutic interventions targeting neurological and vascular pathologies. Additionally, their adaptability to 3D cell culture models allow researchers to simulate complex physiological conditions, enhancing the relevance of in vitro models for disease mechanism studies and drug development.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
