For research use only
| Cat No. | ABC-TC535S |
| Product Type | Human Germ Cell Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Choriocarcinoma |
| Disease | Choriocarcinoma |
| Product Code | BeWo clone b30; BeWo cells subclone b30 |
BeWo Clone b30 cells are placental choriocarcinoma with enhanced monolayer formation, express steroidogenic enzymes, useful for transport studies.
BeWo Clone b30 is a choriocarcinoma cell line derived from a malignant gestational tumor of the fetal placenta (male origin). This epithelial-like adherent cell line proliferates rapidly and exhibits superior monolayer formation compared to parental BeWo, making it ideal for transplacental transport studies. It shows aberrant gene expression, including low baseline levels of steroidogenic enzymes (CYP19A1, HSD11B2), which can be upregulated by forskolin. While tumorigenic, BeWo b30 expresses tight junction proteins and produces placental hormones upon differentiation, enabling studies of placental barrier function and trophoblast biology. Its applications span maternal-fetal transport, drug permeability, and trophoblast differentiation research.
| Product Code | BeWo clone b30; BeWo cells subclone b30 |
| Species | Human |
| Cat.No | ABC-TC535S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Choriocarcinoma |
| Disease | Choriocarcinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Germ Cell Cancer Cell Lines |
BeWo Clone b30 is extensively used as a crucial model for exploring trophoblast behavior, placental physiology, and maternal-fetal interactions. Its ability to form polarized, confluent monolayers makes it especially valuable for investigating transplacental transport mechanisms. Researchers utilize this choriocarcinoma cell line to explore nutrient, drug, and xenobiotic transfer across the placental barrier, as well as to study placental metabolism and hormone production. The model is instrumental in understanding factors that influence maternal-fetal exchange, shedding light on critical aspects of obstetrics, toxicology, and developmental biology.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
