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Species | Bovine |
Cat.No | ABC-H0048X |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Satellite Cell |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Muscle |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Bovine Primary Cells |
Bovine Muscle Satellite Cells are primary myogenic progenitor cells isolated from the longissimus muscle of calves (early passage, P0–P3). These spindle or polygonal-shaped, adherent cells are vital for muscle regeneration, becoming activated in response to injury and fusing into multinucleated fibers. They play a central role in postnatal muscle growth and are widely used in studies of muscular development, muscle-wasting diseases like Duchenne muscular dystrophy, regenerative medicine, and even lab-grown meat. These cells express crucial myogenic markers—Pax7, MyoD, and Myogenin, indicating their stem-like status and differentiation capacity. They are generally chromosomally stable at early passages, though long-term culture may alter this stability.
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Bovine Muscle Satellite Cells are a useful tool used to understand of the composition, development, and growth of skeletal muscle, to enhance the growth and quality of skeletal muscle of cattle in the food industry. Besides, cultured meat (cell-based meat) is an emerging biotechnological field (cell-based meat), that stem cells proliferate and differentiate to produce mature and edible tissue in vitro. Bovine muscle satellite cells are promising candidates for cultured meat if their proliferation and differentiation are optimized.
Bovine Muscle Satellite Cells are stem cells found in the skeletal muscle tissue of cattle. They reside between the muscle fiber and the basal lamina, playing a key role in muscle growth, repair, and regeneration.
These cells are typically isolated through enzymatic digestion of bovine muscle tissue followed by mechanical separation. The process involves the use of collagenase or trypsin to break down the extracellular matrix, followed by cell filtration and purification.
Their primary function is to aid in muscle repair and regeneration. Upon activation, they proliferate and differentiate into myoblasts, which can fuse to form new muscle fibers or repair damaged muscle tissue.
Bovine Muscle Satellite Cells are primarily committed to the myogenic lineage, meaning they predominantly differentiate into myoblasts and then into mature muscle fibers. Their capacity to differentiate into other cell types is limited under normal conditions.
These cells are used in muscle biology research, tissue engineering, regenerative medicine, and agricultural studies focused on improving meat quality, livestock growth, and muscle-related diseases in cattle.