For research use only
| Cat No. | ABC-TC0090 |
| Product Type | Mouse Breast Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Breast |
| Product Code | C127i; C 1271; C-127I; C-127 I; CNC 127I |
Mouse RIII mammary tumour. Non-transformed clone from a RIII mouse. Supernatant fluid is negative for RT activity.
C127I is a murine epithelial carcinoma cell line originating from a spontaneous mammary breast tumor in a female RIII mouse. These cells grow adherently with epithelial-like morphology and exhibit robust proliferation under standard culture conditions. Karyotypic analysis reveals aneuploidy, typical of carcinoma lines. Importantly, C127I supports episomal replication of bovine papillomavirus (BPV) DNA and allows stable transfection with papillomavirus-derived vectors, making it a valuable tool for recombinant protein expression systems. These cells exhibit volume-dependent ATP-conductive, large-conductance anion channels, contributing to regulatory volume decrease (RVD), and rendering them sensitive to hypotonic stress. The cells undergo stringent screening and testing procedures to ensure they are free from contamination by Mycoplasma, fungi, yeast, and bacteria
| Product Code | C127i; C 1271; C-127I; C-127 I; CNC 127I |
| Species | Mouse |
| Cat.No | ABC-TC0090 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Breast |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Breast Cancer Cell Lines |
C127I serves as a versatile model for studies in viral expression systems, oncogenic transformation, and epithelial signaling. It is commonly used for stable transfection with papillomavirus constructs and for visualizing sarcoma virus-induced foci formation in vitro. Additionally, C127I supports high-throughput antiviral compound screening and investigations of ATP-mediated volume regulation and ion channel pharmacology. Due to their epithelial origin and mammary lineage, C127I has significant scientific relevance in breast cancer biology and gene expression research, providing a robust platform for mechanistic and translational studies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
