C4-2B Luciferase Reporter Cell Line

Description

C4-2B Luciferase Reporter Cell Line is a stable model derived from human prostate cancer C4-2B cells, engineered to express luciferase under a constitutive promoter. The luminescence output provides a convenient and sensitive readout for monitoring general transcriptional changes or compound-induced cellular responses. When validated under specific experimental conditions (e.g., monoculture), it can also serve as an indicator of relative cell viability or proliferation. This polyclonal reporter line retains the key characteristics of parental C4-2B cells and is suitable for preliminary compound screening and exploratory studies requiring rapid, luminescence-based assessment of cellular effects. The cells are rigorously tested to ensure they are free of contamination from Syphilis, Mycoplasma, Fungi, Yeast and Bacteria.

Application

• This C4-2B Luciferase Reporter Cell Line is suitable for preliminary compound prescreening using luminescence as a rapid and sensitive readout. It supports applications such as assessing compound-induced cellular effects, monitoring general transcriptional changes, and evaluating cell viability or cytotoxicity. The model provides an efficient platform for early-stage drug discovery and exploratory prostate cancer research workflows.