C57BL/6 Mouse Colonic Epithelial Cells

Description

C57BL/6 Mouse Colonic Epithelial Cells are primary cells isolated from the colonic tissue of pathogen-free laboratory mice. They are primarily localized within the colonic mucosal epithelium. Following primary culture, these cells are cryopreserved. C57BL/6 Mouse Colonic Epithelial Cells maintain intestinal barrier integrity through tight junction proteins (e.g., claudins) and mucus secretion, selectively absorb nutrients and water while excluding pathogens, produce antimicrobial peptides, and modulate immune responses via chemokine signaling. The cells are characterized by antibodies against E-cadherin or ZO-1. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.