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Primary Cells

C57BL/6 Mouse Dermal Epithelial Cells

  • For research use only

Cat No.

ABC-TC3184
Product Type

Mouse Primary Cells
Cell Type

Epithelial
Species

C57BL/6 Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Storage

Liquid Nitrogen

C57BL/6 Mouse Primary Dermal Epithelial Cells from AcceGen are isolated from tissue of pathogen-free laboratory mice.

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  • C57BL/6 Mouse Dermal Epithelial Cells
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/6 Mouse Dermal Epithelial Cells

Description

C57BL/6 Mouse Dermal Epithelial Cells are primary cells isolated from mouse dermal tissue. These cells primarily reside within the stratified squamous epidermis and hair follicle epithelial compartments. Following primary culture, these cells are cryopreserved. These cells are capable of self-renewal and maintain skin barrier integrity. Studies confirm their implication in psoriasis, chronic non-healing diabetic wounds, and cutaneous squamous cell carcinoma (UV-induced Trp53 mutations). Phenotypic characterization confirms expression of epithelial markers E-cadherin and ZO-1, validating their epithelial identity and junctional integrity. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

C57BL/6 Mouse Dermal Epithelial Cells, Mouse Dermal Epithelial Cells, Dermal Epithelial Cells, Epithelial Cells, EpiCs, C57BL/6 Dermal EpiCs
Species

C57BL/6 Mouse
Cat.No

ABC-TC3184
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57BL/6 Mouse Dermal Epithelial Cells can be used as an in vitro model to study the pathogenesis of chronic wound healing disorders in disease conditions such as diabetic foot ulcers and psoriasis. For example, by investigating molecular pathways like TGF-β1/Smad3-mediated epithelial-mesenchymal transition impairment or IL-23/STAT3-driven keratinocyte hyperproliferation, these cells serve as a critical model to elucidate mechanisms of re-epithelialization failure, dysregulated immune responses, and epidermal barrier dysfunction.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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