For research use only
| Cat No. | ABC-TC0101 |
| Product Type | Human Lymphoma Cell Lines |
| Cell Type | Lymphoblast |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Disease | Burkitt’s Lymphoma |
| Product Code | CA-46; CA 46 |
Human Peripheral Blood Monocyte Derived Macrophages are ideal for immunology, inflammation, and macrophage polarization studies using human-derived cells.
CA46 is a human Burkitt lymphoma cell line originally established from the ascitic fluid of a 4-year-old male patient diagnosed with abdominal Burkitt lymphoma. The cells exhibit a round, single-cell morphology and grow in suspension. CA46 is Epstein-Barr virus (EBV) negative but harbors a t(8;14)(q24;q32) chromosomal translocation, resulting in MYC overexpression—a hallmark of Burkitt lymphoma pathogenesis. Karyotypic analysis shows complex chromosomal rearrangements with aneuploidy and additional structural abnormalities. CA46 cells are highly tumorigenic, readily forming aggressive lymphomas when injected into immunodeficient mice. The cell line serves as a reliable model for c-MYC-driven oncogenesis, apoptotic dysregulation, and lymphoid malignancies research, offering a genetically defined, reproducible platform for hematological cancer research. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CA-46; CA 46 |
| Species | Human |
| Cat.No | ABC-TC0101 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Disease | Burkitt’s Lymphoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphoma Cell Lines |
CA46 is ideal for modeling MYC-dependent lymphomagenesis in Burkitt lymphoma and related B-cell malignancies. In laboratory use, researchers commonly use this cell line in apoptosis research, oncogenic signaling pathway analysis, DNA damage response studies, and investigation into chemoresistance mechanisms. It also serves as a platform to explore MYC-targeted therapies and investigate EBV-independent lymphoma progression. Its defined genetic background makes CA46 valuable for high-throughput drug screening, pathway analysis, and biomarker discovery in hematologic cancer research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
