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| Product Code | CCFSTTG1; STTG1 |
| Species | Human |
| Cat.No | ABC-TC0122 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Astrocytic |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Astrocytoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Brain Cancer Cell Lines |
CCF-STTG1 is an astrocytic-like cell line that originates from a 68-year-old White female patient afflicted with astrocytoma, sourced from brain tissue. This human cell line is distinguished by a substantial proportion of tetra-, hexa-, and higher-ploid cells. Remarkably, these cells exhibit significant perinuclear acid phosphatase activity, with glial fibrillary acidic protein present in 70% to 80% of the cellular population. CCF-STTG1 cells demonstrate the constitutive secretion of Apolipoprotein (apo) E in serum-free media. For subculturing, it is advisable to perform a split of sub-confluent cultures, ranging from 1:3 to 1:10, when they reach 70-80% confluence.
Why choose CCF-STTG1 from AcceGen?
CCF-STTG1 cells from AcceGen exhibit exceptional viability and quality, with rigorous daily monitoring to guarantee the absence of bacteria and fungi. They are certified mycoplasma-free through PCR-based assays and verified for their identity via STR analysis, ensuring the utmost reliability in research applications.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The CCF-STTG1 cell line plays a pivotal role in the realm of neuroscience research. It serves as an invaluable model system for the in-depth examination of Apolipoprotein E (apoE) production in astrocytes, affording researchers the capacity to identify cell-specific factors governing apoE synthesis within this context. Furthermore, this cell line assumes significant importance in drug development endeavors, specifically enabling the investigation of how psychotropic agents influence lipid transport and export pathways in cultured human CNS and hepatic cells. It also facilitates the scrutiny of the regulatory mechanisms governing the expression of cholesterol transport proteins, notably ApoE. These multifaceted applications make CCF-STTG1 a cornerstone in advancing our understanding of intricate neurobiological and metabolic pathways.
