CD-1 Mouse Schwann Cells

Description

CD-1 Mouse Schwann Cells are primary glial cells isolated from the sciatic nerves of CD-1 mice. As the principal glial cells of the peripheral nervous system (PNS), Schwann cells play essential roles in axonal insulation and regeneration by forming the myelin sheath. These cells are cryopreserved following isolation and are typically spindle-shaped with adherent growth characteristics. Primary Schwann cells from CD-1 mice display expression of S100β and myelin protein zero (MPZ), which are commonly used markers for phenotypic identification. Importantly, CD-1 Schwann cells have been widely used in studies related to peripheral nerve injury, neuropathic pain, and neuroinflammatory disorders, due to their ability to secrete neurotrophic factors and modulate immune responses. These cells do not undergo indefinite proliferation and should not be subjected to repeated freeze-thaw cycles to maintain viability. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.