For research use only
| Cat No. | ABC-TC0149 |
| Product Type | Mouse Colon Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Rectum |
| Disease | Rectum Cancer |
| Product Code | CMT93-69, CMT93 69, CMT 93/69 |
Mouse C57BL/1CRF rectum carcinoma. Derivative of CMT93. Cells grow in coherent clumps.
CMT 93/69 cell line is a murine carcinoma subline derived from CMT‑93, originally isolated from the rectum of a C57BL/1CRF mouse following long-term MAMA induction. These cells display an epithelial morphology with an adherent growth pattern. The line exhibits a hyperdiploid karyotype with structural chromosome aberrations and occasional polyploidy. CMT 93/69 cells show aggressive tumor formation and enhanced metastatic capacity compared to the parental CMT-93 line, particularly in liver colonization models. In vivo, CMT 93/69 produces large tumors in nude mice and yields liver metastases when implanted in syngeneic models. These features support its utility in studying colorectal cancer progression, tumor invasion, and in vivo metastatic behavior. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.
| Product Code | CMT93-69, CMT93 69, CMT 93/69 |
| Species | Mouse |
| Cat.No | ABC-TC0149 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Rectum |
| Disease | Rectum Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Colon Cancer Cell Lines |
CMT 93/69 is optimized for preclinical colorectal cancer research, particularly in metastasis studies using immunocompetent mouse models. When administered via portal vein or orthotopic implantation, it reliably forms liver tumors, facilitating investigation of metastatic mechanisms, angiogenesis, stemness, and immune evasion. The subline’s epithelial morphology and CD44 expression make it ideal for evaluating oncolytic agents, immunotherapies, and anti-metastatic drugs. Its reproducible growth in syngeneic hosts supports translational studies requiring an intact immune environment and mechanistic insights into colorectal carcinoma progression.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
