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| Product Code | Cynom-K1; CYNOMK-1; CYNOMK1 |
| Species | Monkey |
| Cat.No | ABL-TC0757 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Skin |
| Biosafety Level | 2 |
| Storage | Liquid Nitrogen |
| Product Type | Monkey Skin Cell Lines |
CYNOM-K1 is a non-human primate fibroblast-like cell line established from the skin tissue of a cynomolgus monkey embryo (Macaca fascicularis) at the gestational stage, typical of mid-to-late term harvests. These cells are non-tumorigenic and non-metastatic, as shown by lack of tumor formation in immunocompromised mice. Morphologically, they are adherent and exhibit spindle-shaped fibroblast characteristics, and proliferate well in monolayer cultures. Their primary application is as a highly susceptible substrate for attenuated Sabin Poliovirus strains, supporting the replication of all three viral types. The line has also been utilized in nucleic acid therapeutics research, notably in studies where CEBPA-51 saRNA was used to activate transcription of the CCATT/enhancer binding protein alpha (CEBPA). Although comprehensive karyotype analysis and mutation profiling have not been widely reported, these cells are generally considered genetically stable under recommended culture conditions.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
CYNOM-K1 has broad applications in genetic and vector research. It is used to evaluate hematopoietic cell transduction efficiency via chimeric lentiviral vectors, as well as for assessing the transduction efficiencies of adeno-associated virus vectors through synthetic cell-permeable peptides. Furthermore, researchers can extract genomic DNA from CYNOM-K1, allowing analysis of historical and contemporary genetic variation. These diverse applications make CYNOM-K1 a valuable and essential tool for advancing our understanding of genetic mechanisms and gene delivery techniques.
