For research use only
| Cat No. | ABC-TC0264 |
| Product Type | Human Bone Cancer Cell Lines |
| Cell Type | Fibroblast-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone |
| Disease | Osteosarcoma |
| Product Code | G 292 Clone A 141B1; G-292, clone A141B1; G292CLONEA141B1; G-292; G292 |
Osteosarcoma
G-292 clone A141B1 is a human osteosarcoma cell line isolated from the bone of a White, 9-year-old, female patient with osteosarcoma. G-292 clone A141B1 cells exhibit fibroblast-like morphology and adherent culture properties. They show the type B phenotype for G6PD and the karyotype is subtetraploid with chromosome markers. Cytogenetic analysis of the cells reveals the presence of a p53 mutation. They express Epidermal growth factor (EGF) and demonstrate moderate tumorigenicity. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | G 292 Clone A 141B1; G-292, clone A141B1; G292CLONEA141B1; G-292; G292 |
| Species | Human |
| Cat.No | ABC-TC0264 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone |
| Disease | Osteosarcoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Bone Cancer Cell Lines |
G-292 clone A141B1 cell line serves as a critical in vitro model for drug screening and molecular pathway analysis in bone cancer research. Its inclusion in large-scale oncology initiatives like the Cancer Cell Line Encyclopedia (CCLE) and Cancer Dependency Map (DepMap) enables high-throughput pharmacogenomic profiling to identify therapeutic vulnerabilities. These applications directly support preclinical target validation and biomarker discovery for novel osteosarcoma treatments.
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