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Stem Cells

HighQC™ B129 Mouse Lung Mesenchymal Stem Cell

  • For research use only

Cat No.

ABC-SC0043T
Product Type

Animal Mesenchymal Stem Cells
Cell Type

Mesenchymal Stem Cell
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lung
Disease

Normal
Storage

Liquid Nitrogen

Mouse Lung Mesenchymal Stem Cells are derived from the lung tissues of pathogen-free laboratory adult B129 mice.

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  • HighQC™ B129 Mouse Lung Mesenchymal Stem Cell
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Home | Stem Cells | Mesenchymal Stem Cells (MSC) | HighQC™ B129 Mouse Lung Mesenchymal Stem Cell

Description

HighQC™ B129 Mouse Lung Mesenchymal Stem Cells (MSCs) are derived from the lung tissues of adult B129 mice. The cells exhibit a characteristic fibroblast-like, spindle-shaped morphology in standard culture conditions. During lung injury, the bioactive lipid lysophosphatidic acid (LPA) is released from numerous cells, which activates the LPAR1 receptor on lung-resident MSCs (LR-MSCs), causing the LR-MSCs to migrate and differentiate into fibroblasts. Their defined phenotype and involvement in fibrogenic signaling make them ideal for studying mesenchymal contributions to lung pathophysiology. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ B129 Mouse Lung Mesenchymal Stem Cell, B129 Lung MSC, B129-mL-MSC, Mouse Lung MSC
Species

Mouse
Cat.No

ABC-SC0043T
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Mesenchymal Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lung
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Animal Mesenchymal Stem Cells

Application

  • HighQC™ B129 Mouse Lung Mesenchymal Stem Cells serve as an in vitro model to study pulmonary fibrosis pathogenesis and evaluate therapeutic agents for lung diseases. For example, analyzing their response to TGF-β-mediated activations helps clarify the molecular mechanisms driving extracellular matrix deposition in idiopathic pulmonary fibrosis. This enables drug screening of anti-fibrotic compounds and investigation of regenerative repair pathways, aiding development of targeted interventions for respiratory disorders.​

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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