HighQC™ C57BL/6 Mouse Embryonic Fibroblasts

Description

HighQC™ C57BL/6 Mouse Embryonic Fibroblasts (MEFs) are primary fibroblast cells isolated from tissue of pathogen-free laboratory mice. Morphologically, they display a characteristic spindle-shaped or stellate fibroblast-like appearance. The cells express the fibroblast marker FSP1/S100A4. Functionally, these cells play a critical role in extracellular matrix production, paracrine signaling, and stromal support. As embryonic-stage fibroblasts, MEFs actively participate in tissue morphogenesis and organogenesis by regulating cell–cell and cell–matrix interactions during development. They also contribute to the modulation of local signaling microenvironments through the secretion of growth factors, cytokines, and extracellular matrix components. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.