HighQC™ Human Embryonic Stem Cell

Description

Human Embryonic Stem Cells (ESCs) are derived from the inner cell mass of the human blastocyst. These pluripotent cells possess an extraordinary ability for continuous self-renewal under appropriate culture conditions, generating identical undifferentiated progeny. When transplanted into immunodeficient mice, human ESCs form benign teratomas containing well-organized tissues derived from all three germ layers—ectoderm, mesoderm, and endoderm. These tissues can include structures such as skin, muscle, neurons, and even teeth, offering a powerful in vitro model to study early human development and cellular differentiation.

Application

• Human Embryonic Stem Cells (ESCs) hold immense promise across multiple domains of biomedical research and clinical development. In regenerative medicine, they provide the foundation for tissue engineering and the generation of functional organs, offering new therapeutic possibilities for degenerative conditions. Their ability to differentiate into specialized cell types supports cell replacement therapies aimed at treating diseases such as Parkinson’s disease, type 1 diabetes, and spinal cord injuries. In the pharmaceutical field, ESC-derived models play a critical role in drug discovery and toxicology, allowing for more accurate screening of drug efficacy and safety in human-relevant systems. ESCs also serve as indispensable tools in genetic and developmental research, offering insights into inherited disorders and early embryonic processes. Moreover, their robust DNA repair mechanisms make them valuable for studying genome stability and advancing personalized medicine strategies.