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HighQC™ Human IPS Cell (SOD1 Mutation/ A4V)

  • For research use only

Cat No.

ABC-SC0004T
Product Type

Human iPSCs
Cell Type

Induced Pluripotent Stem Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Storage

Liquid Nitrogen

Induced Pluriopotent Stem Cells (iPSCs) SOD1 Mutation/ A4V

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  • HighQC™ Human IPS Cell (SOD1 Mutation/ A4V)
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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Induced Pluripotent Stem Cells (iPSCs) | HighQC™ Human IPS Cell (SOD1 Mutation/ A4V)

Description

HighQC™ Human IPS Cells (SOD1 Mutation/A4V) are induced pluripotent stem cells (iPSCs) derived from donor somatic cells. The cells exhibit typical pluripotent stem cell morphology, including high nuclear-to-cytoplasmic ratios, prominent nucleoli, and tightly packed colonies with defined edges. These cells are generated by transducing four transcription factors, Sox2, Oct4, Klf4, and c-Myc, into somatic cells. The SOD1 A4V mutation, a well-known pathogenic variant in familial ALS, is verified by sequencing and remains stable in culture. These cells can differentiate into three germ layers in vitro and in vivo. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ Human IPS Cell (SOD1 Mutation/ A4V), Human iPSC-SOD1-A4V, hIPSC-SOD1, Human Induced Pluripotent Stem Cells SOD1
Species

Human
Cat.No

ABC-SC0004T
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Induced Pluripotent Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Storage

Liquid Nitrogen
Product Type

Human iPSCs

Application

  • HighQC™ Human IPS Cells (SOD1 Mutation/ A4V) serve as a genetically accurate disease-relevant model for Amyotrophic Lateral Sclerosis (ALS) pathogenesis studies. They enable studies of motor neuron degeneration mechanisms, oxidative stress responses, and neuroinflammation pathways, and support drug screening initiatives and gene correction strategies targeting SOD1-related pathology. These cells are available as a SOD1 A4V mutation human iPSC, representing an ALS model SOD1 mutant iPSC and a well-characterized human iPSC line SOD1 A4V for disease-specific research and therapeutic development.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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